The term "liver disease" applies to many conditions that stop the liver from working or prevent it from functioning well. Abdominal pain or swelling, yellowing of the skin or eyes (jaundice), or abnormal results of liver function tests may suggest you have liver disease.
Related topics include:
- Alpha-1 anti-trypsin deficiency
- Amebic liver abscess
- Autoimmune hepatitis
- Biliary atresia
- Cirrhosis
- Coccidioidomycosis
- Delta virus (hepatitis D)
- Drug-induced cholestasis
- Metabolic dysfunction-associated steatotic liver disease (MASLD)
- Hemochromatosis
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Liver disease due to alcohol
- Primary biliary cholangitis (PBC)
- Pyogenic liver abscess
- Reye syndrome
- Sclerosing cholangitis
- Wilson disease
References
Lidofsky SD. Jaundice. In: Chung RT, Rubin DT, Wilcox CM, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 12th ed. Philadelphia, PA: Elsevier; 2026:chap 22.
Martin P. Approach to the patient with liver disease. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 132.
Pratt DS. Liver chemistry and function tests. In: Chung RT, Rubin DT, Wilcox CM, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 12th ed. Philadelphia, PA: Elsevier; 2026:chap 75.
Review Date 4/27/2026
Updated by: Todd Eisner, MD, Private practice specializing in Gastroenterology in Boca Raton and Delray Beach, Florida at Gastroenterology Consultants of Boca Raton. Affiliate Assistant Professor, Florida Atlantic University School of Medicine. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.