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The most common cause of knee damage that leads to knee replacement is osteoarthritis. Osteoarthritis is a degenerative disease of the bones of the knee. It causes the surfaces of the knee joint to become irregular and rough, preventing smooth painless motion of the knee joint.
Knee joint replacement may be recommended for:
Knee osteoarthritis, or arthritis, which causes knee pain that has failed to respond to conservative therapy (NSAID medication for 6 months or more)
Decreased knee function caused by arthritis
Inability to work because of knee pain
Inability to sleep through the night because of knee pain
Inability to walk more than 3 blocks because of knee pain
Loose knee prosthesis
Some knee fractures
Review Date 10/9/2025
Updated by: Diane M. Horowitz, MD, Rheumatology and Internal Medicine, Northwell Health, Great Neck, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
