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Pokeweed poisoning

Pokeweed is a flowering plant. Pokeweed poisoning occurs when someone eats pieces of this plant.

This article is for information only. DO NOT use it to treat or manage an actual poison exposure. If you or someone you are with has an exposure, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.

Poisonous Ingredient

Poisonous ingredients include:

  • Phytolaccatoxin
  • Phytolaccigenin

Where Found

All parts of the Pokeweed plant are toxic to humans. The highest amounts of poison are found in the roots, leaves, and stems. Small amounts are in the fruit.

Cooked berries and leaves (cooked twice in separate water) can technically be eaten. However, this is never recommended because there is no guarantee that they are safe. The roots should never be eaten.

Symptoms most often appear within 6 hours of ingestion.

Symptoms

Symptoms may include:

Home Care

Seek immediate medical help. DO NOT make a person throw up unless told to do so by poison control or a health care provider.

Before Calling Emergency

Get the following information:

  • Person's age, weight, and condition
  • Time it was swallowed
  • Amount swallowed
  • Name and part of the plant that was eaten, if known

Poison Control

The local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

You can also get online poison help now at Poisonhelp.org. Just enter the product, poison, or medicine to get expert help.

What to Expect at the Emergency Room

The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate.

Tests that may be done include:

Treatment may include:

  • Activated charcoal
  • Breathing support, including tube through the mouth into the lungs and connected to a breathing machine (ventilator)
  • Fluids through a vein (by IV)
  • Laxatives
  • Medicine to treat the effects of the poison and other symptoms

Outlook (Prognosis)

How well you do depends on the amount of poison swallowed and how quickly treatment is received. The faster you get medical help, the better the chance for recovery.

Deaths have been reported. Improper cooking of leaves or eating some of the roots with the leaves can cause serious poisoning. Eating more than 10 uncooked berries can cause serious problems in children.

DO NOT touch or eat any plant with which you are not familiar. Wash your hands after working in the garden or walking in the woods.

Alternative Names

American nightshade poisoning; Inkberry poisoning; Pigeon Berry poisoning; Pokeberry poisoning; Scoke poisoning; Virginia poke poisoning; Poke salad poisoning

References

Aronson JK. Phytolaccaceae. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier B.V.; 2016:758-758.

Graeme KA. Toxic plant ingestions. In: Auerbach PS, Cushing TA, Harris NS, eds. Auerbach's Wilderness Medicine. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 65.

Higgins T. Wild plant and mushroom poisoning. In: Higgins T, ed. Medicine for the Outdoors. 7th ed. Philadelphia, PA: Elsevier; 2024:422-430.

Meehan TJ. Care of the poisoned patient. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 135.

Nelson LS, Calello DP. Acute poisoning. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 96.

Theobald JL, Corcoran JN. Poisoning. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 94.

Review Date 10/14/2025

Updated by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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