Depilatory poisoning

The harmful ingredients in depilatories are:

• Sodium or calcium hydroxide (alkalis), which are very toxic
• Barium sulfide
• Thioglycolates

There may be other poisonous ingredients in depilatories.

These ingredients are found in various depilatories.

Symptoms of depilatory poisoning include:

• Abdominal pain
• Blurred vision
• Breathing difficulty
• Burning pain in the throat
• Burns to the eye (if depilatory cream gets in the eye)
• Collapse (shock)
• Coma (decreased level of consciousness and lack of responsiveness)
• Diarrhea (watery, bloody)
• Drooling
• Inability to walk normally
• Low blood pressure
• No urine output
• Rash
• Slurred speech
• Stupor (decreased level of consciousness)
• Vomiting

Seek medical help right away. Do not make the person throw up unless poison control or a health care provider tells you to.

If the person swallowed the depilatory, give them water or milk right away, unless a provider tells you not to. Do not give water or milk if the person has symptoms that make it hard to swallow. These include:

• Vomiting
• Convulsions
• A decreased level of alertness

Have this information ready:

• Person's age, weight, and condition
• Name of the product (ingredients, if known)
• Time it was swallowed
• Amount swallowed

The local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

You can also get online poison help now at Poisonhelp.org. Just enter the product, poison, or medicine to get expert help.

Take the container with you to the hospital, if possible.

Your provider will measure and monitor your vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated.

Tests that may be done include:

• Blood and urine tests
• Chest x-ray
• Electrocardiogram (ECG)
• Endoscopy -- camera placed down the throat to check for burns in the esophagus and stomach

Treatment may include:

• Breathing support, including tube through the mouth into the lungs and breathing machine (ventilator)
• Fluids through a vein (by IV)
• Surgery to remove burned skin (debridement)
• Washing of the skin (irrigation), every few hours or for several days

This can be a very serious poisoning. How well someone does depends on how much poison they swallowed and how quickly they receive treatment. The faster medical help is given, the better the chance for recovery.

Extensive damage to the mouth, throat, and stomach is possible. How someone does depends on how much of this damage there is. This damage can continue to develop in the esophagus (food pipe) and stomach for several weeks after the product is swallowed. If a hole forms in these organs, severe bleeding and infection can occur.

Hair removal agents poisoning

Hoyte C. Caustics. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 143.

Meehan TJ. Care of the poisoned patient. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 135.

Nelson LS, Calello DP. Acute poisoning. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 96.

Theobald JL, Corcoran JN. Poisoning. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 94.

Updated by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.