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CSF test for syphilis

CSF test for syphilis

Overview

Venereal disease research laboratory test (VDRL) of the cerebrospinal fluid (CSF) is used to screen for syphilis. CSF is a clear fluid that circulates in the space surrounding the spinal cord.

Review Date 8/29/2024

Updated by: Jatin M. Vyas, MD, PhD, Roy and Diana Vagelos Professor in Medicine, Columbia University Vagelos College of Physicians and Surgeons, Division of Infectious Diseases, Department of Medicine, New York, NY. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.