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Lyme disease

Lyme disease

Overview

Lyme disease is an acute inflammatory disease characterized by skin changes, joint inflammation and symptoms similar to the flu that is caused by the bacterium Borrelia burgdorferi. Lyme disease is transmitted by the bite of a deer tick. Symptoms sometimes improve in 3 to 4 weeks, but secondary or tertiary disease may develop if initial infection is not treated.

Review Date 3/1/2026

Updated by: Jatin M. Vyas, MD, PhD, Roy and Diana Vagelos Professor in Medicine, Columbia University Vagelos College of Physicians and Surgeons, Division of Infectious Diseases, Department of Medicine, New York, NY. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.