Dipivefrin Ophthalmic

Dipivefrin ophthalmic is no longer available in the United States.

Ophthlamic dipivefrin is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Dipivefrin works by decreasing the pressure in the eye.

Ophthalmic dipivefrin comes as a solution (liquid) to instill in the eye. Dipivefrin eye drops are usually applied every 12 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use dipivefrin eye drops exactly as directed. Do not use more or less of them or use them more often than prescribed by your doctor.

Dipivefrin eye drops control glaucoma but do not cure it. Continue to use dipivefrin eye drops even if you feel well. Do not stop using dipivefrin eye drops without talking to your doctor.

To instill the eye drops, follow these steps:

1. Wash your hands thoroughly with soap and water.
2. Check the dropper tip to make sure that it is not chipped or cracked.
3. Avoid touching the dropper tip against your eye or anything else; eye drops and droppers must be kept clean.
4. While tilting your head back, pull down the lower lid of your eye with your index finger to form a pocket.
5. Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it.
6. Brace the remaining fingers of that hand against your face.
7. While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.
8. Close your eye for 2 to 3 minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids.
9. Place a finger on the tear duct and apply gentle pressure.
10. Wipe any excess liquid from your face with a tissue.
11. If you are to use more than one drop in the same eye, wait at least 5 minutes before instilling the next drop.
12. Replace and tighten the cap on the dropper bottle. Do not wipe or rinse the dropper tip.
13. Wash your hands to remove any medication.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Before using dipivefrin eye drops,

• tell your doctor and pharmacist if you are allergic to dipivefrin, epinephrine, sulfites, or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
• tell your doctor if you have or have ever had high blood pressure, heart or blood vessel disease, irregular heartbeat, or asthma.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using dipivefrin eye drops, call your doctor immediately.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are using dipivefrin eye drops.
• if you are using another topical eye medication, instill it at least 10 minutes before or after you instill dipivefrin eye drops.

Instill the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill a double dose to make up for a missed one.

Dipivefrin eye drops may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• eye irritation or discomfort
• swelling or pain of the eye
• blurred vision
• increased sensitivity to light and glare

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

• fast or irregular heartbeat
• chest pain
• wheezing
• difficulty breathing

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature in the dark and away from excess heat and moisture (not in the bathroom). If this happens, do not use the medication; obtain a new supply.

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.

Keep all appointments with your doctor. Your doctor will order certain eye tests to check your response to dipivefrin eye drops.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

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