Ergocalciferol

Ergocalciferol is used in the treatment of hypoparathyroidism (condition in which the body does not produce enough parathyroid hormone), refractory rickets (softening and weakening of bones that does not respond to treatment), and familial hypophosphatemia (rickets or osteomalacia caused by an inherited condition with a decreased ability to break down vitamin D in the body). Ergocalciferol is in a class of medications called vitamin D analogs. It works by helping the body to use more of the calcium found in foods or supplements.

Ergocalciferol comes as a capsule to take by mouth. It is usually taken once daily. Take ergocalciferol at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ergocalciferol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the capsules whole; do not chew or crush them.

Your doctor may change your dose depending on your body's response to ergocalciferol.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking ergocalciferol,

• tell your doctor and pharmacist if you are allergic to ergocalciferol, aspirin, tartrazine (a yellow dye in some processed foods and drugs), any other medications, or any of the ingredients in ergocalciferol capsules. Ask your pharmacist for a list of the ingredients.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking ergocalciferol. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• the following nonprescription products may interact with ergocalciferol: mineral oil; vitamin D supplements; calcium supplements. Be sure to let your doctor and pharmacist know that you are taking these medications before you start taking ergocalciferol. Do not start any of these medications while taking ergocalciferol without discussing with your healthcare provider.
• tell your doctor if you have high blood levels of calcium and vitamin D, an abnormal sensitivity to high levels of vitamin D, or if you have malabsorption syndrome (problems absorbing food). Your doctor will probably tell you not to take ergocalciferol.
• tell your doctor if you have or have ever had kidney or liver disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ergocalciferol, call your doctor.

Ergocalciferol will work only if you also get the right amount of calcium from the foods you eat. If you get too much calcium from foods, you may experience serious side effects from taking ergocalciferol. If you do not get enough calcium from foods, ergocalciferol will not control your condition. Your doctor will tell you which foods are good sources of calcium and how many servings you need each day. If you find it difficult to eat enough of these foods, tell your doctor. In that case, your doctor can prescribe or recommend a calcium supplement.

Your doctor may also prescribe a low-phosphate diet during your treatment with ergocalciferol. Follow these directions carefully.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Ergocalciferol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• pale skin
• tiredness

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

• feeling tired, difficulty thinking clearly, loss of appetite, nausea, vomiting, constipation, increased thirst, increased urination, or weight loss
• drowsiness
• muscle aches, stiffness, and weakness

Ergocalciferol may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach. https://www.upandaway.org

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

• loss of appetite
• nausea
• weakness
• weight loss
• muscle aches and stiffness
• constipation
• pale skin
• increased urination (especially at night) or increased thirst
• intellectual disability

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before and during your treatment with ergocalciferol.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

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