Ceftaroline Injection

Ceftaroline injection is used to treat some types of infections caused by bacteria. Ceftaroline is in a class of medications called cephalosporin antibiotics. It works by killing bacteria.

Antibiotics such as ceftaroline injection will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Ceftaroline injection comes as a powder to be added to fluid and given through a needle or catheter placed in your vein. It is injected intravenously (into a vein) over a period of 5 to 60 minutes every 8 to 12 hours. The length of your treatment depends on the type of infection you have and how your body responds to the medication.

You may receive ceftaroline injection in a hospital or you may give the medication at home. If you will be using ceftaroline injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.

You should begin to feel better during the first few days of your treatment with ceftaroline injection. If your symptoms do not improve or get worse, call your doctor.

Use ceftaroline injection until you finish the prescription, even if you feel better. If you stop using ceftaroline injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before using ceftaroline injection,

• tell your doctor or pharmacist if you are allergic to this medication, any part of this medication, or any other medications, foods or substances. Tell your doctor or pharmacist about the allergy and what symptoms you had.
• tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• tell your doctor if you have or have ever had kidney disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using ceftaroline injection, call your doctor.

Unless your doctor tells you otherwise, continue your normal diet.

Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.

Ceftaroline injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• diarrhea, nausea, vomiting, constipation
• redness or irritation at the injection site

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

• watery or bloody stools, stomach cramps or fever during treatment or for up to two or more months after stopping treatment
• itching, rash, hives
• difficulty breathing or swallowing; swelling of the tongue or throat; shortness of breath
• extreme tiredness
• pale skin
• fast or irregular heartbeat
• chest pain
• cold hands and feet
• dizziness
• tiredness, drowsiness, confusion, and slow thinking
• seizures

Ceftaroline may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (https://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Your healthcare provider will tell you how to store your medication. Store your medication only as directed. Make sure you understand how to store your medication properly.

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location – one that is up and away and out of their sight and reach https://www.upandaway.org

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website https://goo.gl/c4Rm4p for more information.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to ceftaroline injection.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking ceftaroline injection.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish ceftaroline injection, call your doctor.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

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